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41 items found for "opioid receptor"
- Last of the Laowai Part II: The Final Resort
Really, that life is beginning to crumble as I stumble back into opioid and benzo addiction, but I'm
- July 2024 Life Updates: A Sick, Sad Summer
. *** I've been in opioid withdrawal for weeks. For reasons detailed here and here , I detest being on opioid maintenance. I'm constantly under the influence of a powerful opioid, and the sickest part of it is that I can't even I have all of the typical, pernicious opioid withdrawal symptoms, but I also have a profound, sapping For others, I've functioned as a sort of opioid / benzo withdrawal doula, guiding them through the process
- Red, White, and Bummed-Out Blues: Uneasy Independence Day Reflections on American Politics in 2024 and American Decline in General
Since 1999, more than 560,000 Americans have died of opioid overdoses. fact that they knowingly marketed a defective "extended-release" formulation of a massive dose of an opioid In terms of our use of such substances, in 2017, after opioid prescription had already been cracked down on hard for several years, there were still enough opioids prescribed to keep every American man, woman And, as awful as the opioid epidemic has been, American consumption of other legal, prescription, and
- I Was Never "Normal": What It's Like to Be a Drug Addict Who Hasn't Started Using Yet
But my God: From the start, I knew that opioids were different. If there were a soundtrack to the sh*tshow that is my life, then the track for that first opioid experience Opioids ushered me through the gates of paradise. I was home. I was free. I was fine.
- The More I See, The Less I Know: Three Flawed Models of Addiction
Using the example of opioid addiction, at best we can currently use maintenance therapies like buprenorphine and methadone - or even treatment with antagonists like naltrexone - to modulate receptor dynamics For severe opioid addiction, on the other hand, even with opioid maintenance treatment, perhaps only political views (2) Signs that you're becoming dependent on and perhaps even addicted to your benzo or opioid
- The Selfish Genes That Prospered: The Evolution of Addiction
I've seen values of 500 to 750% for opioids. At the molecular level, these differences come partly from variations in dopamine receptors. Different people have variations on the gene that specifies how to make this receptor, and because of this, our midbrain reward system can be more or less reactive (less reactive dopamine receptors mean Intriguingly, human migration patterns correlate with dopamine receptor genetics.
- Medical-Grade Xylazine Product Review: Pure Garbage With No Place in the Recreational Pantheon
The second frightening thing about xylazine is that because it is not an opioid, the opioid antagonist
- Snapshot: Does Anything Ever Really Change?
Treatment professionals who specialize in opioid addiction are starting to talk about recovery as a cycle
- Enough, Cat Marnell (Book Review)
reminded of the day when pursuing my calling to become a doctor while wrestling with the demons of my opioid
- I Was Simon Song
In addition, I recount some wild stories stemming from my relapse into prescription opioid and benzo sleeping on a mattress on the floor of my Williamsburg sublet, which was stained with the acrid sweat of opioid
- Nietzsche's Eternal Recurrence: What If You Had to Live Your Life Over and Over Again?
My initial reaction is that my worst episode of combined opioid, benzo, and barbiturate withdrawal would
- Threats from Drug Dealers: How to Tell Who Will Really Mess You Up
After feeling out that he was a little sketchy, I mentioned to him that I was sick from opioid withdrawal